Peripheral opioid receptor antagonists and uses thereof

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United States of America Patent

PATENT NO 8546418
APP PUB NO 20110190331A1
SERIAL NO

12593619

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Abstract

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The present invention provides a compound of formula I: wherein R1, R2, R2′ and X′ are as defined and described herein, methods of manufacture thereof and compositions thereof, useful for example as peripheral mu opioid receptor antagonists in treatment of side effects of opioid administration.

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Patent Owner(s)

Patent OwnerAddress
PROGENICS PHARMACEUTICALS INC777 OLD SAW MILL RIVER ROAD TARRYTOWN NY 10591

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Avey, Alfred A Eugene, US 5 35
Chandrasekaren, Appavu Plainsboro, US 2 15
Doshan, Harold D Riverside, US 8 126
Perez, Julio Tarrytown, US 20 288
Rotshteyn, Yakov Monroe, US 7 132

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