Process for the stereoselective enzymatic hydrolysis of 5-methyl-3-nitromethyl-hexanoic acid ester

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United States of America Patent

PATENT NO 8546112
APP PUB NO 20110165636A1
SERIAL NO

12993132

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Abstract

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The present invention relates to processes for the preparation of 5-methyl-3-nitromethyl-hexanoic acid ester and its salts. Also disclosed are processes for the preparation of 5-methyl-3-nitromethyl-hexanoic acid salt and a process for the preparation of 3-(aminomethyl)-5-methylhexanoic acid. (S)-5-Methyl-3-nitromethyl-hexanoic acid or (R)-5-methyl-3-nitromethyl-hexanoic acid in enantioenriched form or enantiopure form as well as salts thereof, (S)-5-methyl-3-nitromethyl-hexanoic acid ester or (R)-5-methyl-3-nitromethyl-hexanoic acid ester in enantioenriched form or enantiopure form and a compound, namely Formula (XIII), in racemic form, enantioenriched form or enantiopure form are also disclosed.

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Patent OwnerAddress
SANDOZ AGCENTRALBAHNSTRASSE 4 4051 BASEL 4051

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Albert, Martin Kundl, AT 9 11
Berger, Andreas Kundl, AT 93 880
De, Souza Dominic Kundl, AT 10 11
Luschnig, Daniel Graz, AT 5 17
Osl, Doris Kundl, AT 1 0
Remler, Peter Graz, AT 2 0
Riethorst, Waander Kundl, AT 4 21
Salchenegger, Joerg Kundl, AT 3 0
Schwab, Helmut Graz, AT 32 322
Zepeck, Ferdinand Kundl, AT 4 1

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