Processes for the preparation of phosphatide salts

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United States of America Patent

PATENT NO 8546104
APP PUB NO 20110212922A1
SERIAL NO

12700073

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Abstract

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The present invention discloses processes a process for the preparation of phosphatide-salt complexes, the process including the steps of: using at least one raw material lecithin as a substrate; and enzymatically processing at least one raw material lecithin with phospholipase-D, racemic or enantiomerically-pure serine, and/or amine in an aqueous carboxylate-salt-complex solution, wherein the step of processing is performed in a single-phase reaction environment, to produce phosphatide-salt complexes having a structural fatty-acid chain derived from at least one raw material lecithin. Preferably, the step of processing is performed at a pH in the range of about 4.5-8.0 at a temperature in the range of about 25-60° C. Preferably, the aqueous carboxylate-salt-complex solution is formed from an aqueous solution of a carboxylic acid with a chain length of C2-C8 and a salt in an approximately 1:2 (weight per weight) acid-to-salt ratio.

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Patent Owner(s)

Patent OwnerAddress
LIPOGEN LTD34372 HAIFA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Rutenberg, David Haifa, IL 11 21

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