Targets, including Yap1, for antifungal drug discovery and therapy
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United States of America Patent
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Sep 24, 2013
Grant Date -
Feb 10, 2011
app pub date -
Dec 10, 2007
filing date -
Dec 8, 2006
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Abstract
The present invention is based on the discovery of a two organism model system that can be used to identify virulence factors. The system is also useful in the process of drug delivery. More specifically, we have established valid fungal infection in caenorhabditis elegans with an invading pathogen, the yeast Saccharomyces cerevisiae. Because both species are genetic model organisms, the assay can be used to identify host and virulence factors involved in such interactions.
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