Methods of treating lupus by administering humanized anti-interleukin 3 receptor alpha chain antibodies

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United States of America Patent

PATENT NO 8535669
APP PUB NO 20130084282A1
SERIAL NO

13579886

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Abstract

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The present disclosure provides a method for treating lupus, Sjörgen's syndrome or scleroderma, the method comprising administering to the mammal an immunoglobulin which binds an interleukin 3 receptor α (IL-3Rα) chain and which depletes or at least partly eliminates plasmacytoid dendritic cells (p DCs) and basophils to which it binds.

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Patent Owner(s)

Patent OwnerAddress
CSL LIMITEDPARKVILLE VIC 3052

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Busfield, Samantha Brunswick, AU 4 14
Maraskovsky, Eugene Kew, AU 31 363
Nash, Andrew Kew, AU 31 232
Vairo, Gino Luigi Northcote, AU 17 69
Wilson, Nick Brighton East, AU 23 77

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