AAV vectors for in vivo gene therapy of rheumatoid arthritis
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United States of America Patent
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Sep 10, 2013
Grant Date -
May 10, 2007
app pub date -
Sep 1, 2004
filing date -
Sep 1, 2003
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Abstract
The present invention relates to the field of adeno-associated virus (AAV) based gene therapy, in particular in vivo gene therapy, of rheumatoid arthritis (RA). The invention provides recombinant AAV virions being highly efficient in delivering genes encoding therapeutic proteins to the arthritic joints, and method for using such virions in in vivo gene therapy.
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