Anti-platelet membrane glycoprotein VI monoclonal antibody

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United States of America Patent

PATENT NO 8524870
APP PUB NO 20130095120A1
SERIAL NO

13721547

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention provides an antibody which has the following features, its active fragment, or a derivative thereof: a) It specifically binds to human platelet membrane glycoprotein VI (GPVI); b) The function to activate a platelet and/or the function to induce a thrombocytopenia in vivo are low; and c) It at least partially depletes GPVI on the platelet membrane by contacting with a platelet.

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Patent Owner(s)

Patent OwnerAddress
MOCHIDA PHARMACEUTICAL CO LTDTOKYO JAPAN TOKYO METROPOLIS

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Furusako, Shoji Tokyo, JP 32 302
Honda, Motoyasu Tokyo, JP 6 50
Hosaka, Yoshitaka Tokyo, JP 12 138
Hotta, Yumi Tokyo, JP 5 98
Kawahara, Tetsushi Tokyo, JP 9 149
Matsusue, Tomokazu Tokyo, JP 8 122
Naitoh, Katsuki Tokyo, JP 9 103
Shirakawa, Kamon Tokyo, JP 34 305
Takayama, Hiroshi Ibaraki, JP 36 316

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