Process for producing a fraction enriched up to 100% of 3-O-acetyl-11-keto-beta-boswellic acid from an extract containing a mixture of boswellic acids
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United States of America Patent
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Sep 3, 2013
Grant Date -
Apr 15, 2004
app pub date -
Mar 5, 2002
filing date -
Mar 5, 2002
priority date (Note) -
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Abstract
The invention relates to a process for producing a fraction enriched upto 100% of 3-O-acetyl-11-keto-β-boswellic acid. An organic solvent extract of gum resin from Boswellia species is first subjected to oxidation and then acetylation or vice versa. This converts the less potent boswellic acids present in the fraction to AKBA. This treated fraction is subjected to further purification and separation by chromatographic separation techniques to enhance its purity and to remove contaminants therefrom. This process provide an access to a fraction enriched in 10-100% AKBA for therapeutic applications.
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