Compounds and compositions as kinase inhibitors
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United States of America Patent
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Aug 27, 2013
Grant Date -
Aug 4, 2011
app pub date -
Apr 3, 2009
filing date -
Apr 7, 2008
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Abstract
The invention relates to triazine and pyrimidine derivatives having Formula (1) or (2), and methods for using such compounds. For example, the compounds of the invention may be used to treat, ameliorate or prevent a condition which responds to inhibition of anaplastic lymphoma kinase (ALK) activity, c-ros oncogene (ROS), insulin-like growth factor (IGF-IR), and/or insulin receptor (InsR) or a combination thereof.
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