Method of identifying an inhibitor of the prostanoid EP4 receptor

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United States of America Patent

PATENT NO 8513027
APP PUB NO 20080247954A1
SERIAL NO

11976945

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Abstract

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The present invention provides for the treatment of primary headache disorders, particularly migraine, using antagonists of the EP4 receptor for prostaglandin E2. Particular EP4 receptor antagonists include azole compounds of formula (I):

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ASTERAND UK ACQUISITION LIMITED6-8 UNDERWOOD STREET LONDON N1 7JQ

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Baxter, Gordon S Hertfordshire, GB 6 32
Coleman, Robert A Hertfordshire, GB 15 124
Tilford, Nicholas Hertfordshire, GB 2 5

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