Sustained release micropellets and process for producing the same
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United States of America Patent
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Aug 20, 2013
Grant Date -
Jan 8, 2009
app pub date -
Aug 16, 2007
filing date -
Aug 17, 2001
priority date (Note) -
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Abstract
Sustained release micropellets showing a stable controlled-release of a drug without being affected by the changes in pH value etc., characterized by being produced by coating core particles with a layer containing a water-soluble drug and further forming a film layer containing a water-insoluble polymer compound and a plasticizer on the thus obtained particles, locating a water-soluble filler layer between the water soluble drug-containing layer and the film layer, and having an average particle size of 300 μm or less; medicinal compositions containing these micropellets; and a process for producing the same.
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