Benzofuran type derivatives, a composition comprising the same for treating or preventing cognitive dysfunction and the use thereof
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United States of America Patent
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Aug 13, 2013
Grant Date -
Sep 27, 2012
app pub date -
Jun 5, 2012
filing date -
Oct 2, 2006
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Abstract
The present invention relates to the novel benzofuran derivatives, the preparation thereof and the composition comprising the same. The benzofuran derivatives of the present invention showed potent inhibiting activity of beta-amyloid aggregation and cell cytotoxicity resulting in stimulating the proliferation of neuronal cells as well as recovering activity of memory learning injury caused by neuronal cell injury using transformed animal model with beta-amyloid precursor gene, therefore the compounds can be useful in treating or preventing cognitive function disorder.
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