Tetrahydroprotoberberine compounds, the synthetic method and the use thereof

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United States of America Patent

PATENT NO 8501762
APP PUB NO 20090149488A1
SERIAL NO

11988441

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention relates to tetrahydroprotoberberines of the formula (I) and the physiologically acceptable salts thereof. The invention also relates to the use of the compounds of the formula (I) or pharmaceutically acceptable salts thereof for preparing a pharmaceutical composition for the treatment of a medical disorder susceptible to treatment with dopamine receptor ligand, such as schizophrenia.

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Patent Owner(s)

Patent OwnerAddress
SHANGHAI INSTITUTE OF MATERIA MEDICA CHINESE ACADEMY OF SCIENCES201203 555 ZHANGJIANG ROAD ZHANGJIANG PUDONG NEW AREA SHANGHAI SHANGHAI CITY SHANGHAI CITY 201203
TOPHARMAN SHANGHAI CO LTDSHANGHAI 201209

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chen, Xinjian Shanghai, CN 20 28
Jin, Guozhang Shanghai, CN 3 10
Li, Jianfeng Shanghai, CN 76 407
Liu, Aixiang Shanghai, CN 1 10
Pan, Yanjun Shanghai, CN 2 10
Shen, Jingkang Shanghai, CN 22 45
Shen, Jingshan Shanghai, CN 29 32
Yan, Tiema Shanghai, CN 2 33
Zhang, Rongxia Shanghai, CN 11 26
Zhu, Yi Shanghai, CN 173 554

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