Piperidinyl carbamate intermediates for the synthesis of aspartic protease inhibitors

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 8487108
APP PUB NO 20100048636A1
SERIAL NO

12084928

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Abstract

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The present invention is directed to aspartic protease inhibitors. Certain aspartic protease inhibitors of the invention can be represented by the following structural formula or a pharmaceutically acceptable salt thereof. The present invention is also directed to pharmaceutical compositions comprising the disclosed aspartic protease inhibitors. The present invention is further directed to methods of antagonizing one or more aspartic proteases in a subject in need thereof, and methods for treating an aspartic protease mediated disorder in a subject using the disclosed aspartic protease inhibitors.

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Patent Owner(s)

Patent OwnerAddress
VITAE PHARMACEUTICALS INC502 WEST OFFICE CENTER DRIVE FORT WASHINGTON PA 19034

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Baldwin, John J Gwynedd Valley, US 214 2088
Cacatian, Salvacion Blue Bell, US 49 482
Claremon, David A Maple Glen, US 167 2136
Dillard, Lawrence W Yardley, US 55 1025
Flaherty, Patrick T Pittsburgh, US 20 53
Ishchenko, Alexey V Somerville, US 22 60
McGeehan, Gerard Garnet Valley, US 28 172
Simpson, Robert D Wilmington, US 34 299
Singh, Suresh B Kendall Park, US 95 1396
Tice, Colin Ambler, US 8 15
Xu, Zhenrong Horsham, US 57 628
Yuan, Jing Lansdale, US 135 622
Zhao, Wei Eagleville, US 814 5746

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