Nasal calcitonin formulations containing chlorobutanol
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United States of America Patent
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Jul 16, 2013
Grant Date -
Jun 7, 2012
app pub date -
Feb 10, 2012
filing date -
Mar 21, 2003
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Abstract
An aqueous solution of calcitonin suitable for intranasal administration comprised of calcitonin, chlorobutanol at a concentration of less than 0.4% weight/weight, and water and having a pH of less than 4 with the proviso that benzalkonium chloride is not present in the solution. The aqueous solution of calcitonin can be used to treat osteoporosis, Paget's bone disease and hypercalcemia.
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