Modified soluble FGF receptor Fc fusions method

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United States of America Patent

PATENT NO 8481487
APP PUB NO 20120195851A1
SERIAL NO

13348297

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The invention relates to modified soluble FGF receptor Fc fusions comprising a fusion of a soluble fragment or domain of the FGF receptor part (targeting or binding moiety) with an Fc region of an immunoglobulin part (effector function moiety), having improved biological activity including ADCC/CDC activities, compositions containing them, and method of producing such modified soluble FGF receptor Fc fusion molecules.

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Patent Owner(s)

Patent OwnerAddress
AVENTIS PHARMA S A20 AVENUE RAYMOND ARON ANTONY CEDEX 92165

International Classification(s)

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  • 2012 Application Filing Year
  • A61K Class
  • 11964 Applications Filed
  • 9694 Patents Issued To-Date
  • 81.03 % Issued To-Date
Click to zoom InYear of Issuance% of Matters IssuedCumulative IssuancesYearly Issuances201220132014201520162017201820192020202120222023202420250255075100

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Blanche, Francis Paris, FR 54 371
Cameron, Béatrice Paris, FR 24 124
Nesbit, Mark Paris, FR 8 48
Nicolazzi, Céline Paris, FR 9 6
Sordello, Sylvie Paris, FR 3 21
Trombe, Marc Paris, FR 3 21

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11.5 Year Payment $7400.00 $3700.00 $1850.00 Jan 9, 2025