Process for production of camptothecin derivative
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United States of America Patent
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Jul 2, 2013
Grant Date -
Jun 7, 2012
app pub date -
Apr 27, 2007
filing date -
Apr 27, 2006
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Abstract
Disclosed is a process for production of 7-ethyl-10-[4-(1-piperidino)-1-piperidino]-carbonyloxycamptothecin from a camptothecin composition containing 18,19-dehydrocamptothecin without producing any vinyl form of the compound. The process is characterized by catalytically reducing at least one compound selected from a compound (1) and others in the process of producing a compound (5) from a composition containing the compound (1).
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