Methods and compositions for assaying homocysteine

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 8476034
APP PUB NO 20080305507A1
SERIAL NO

11969803

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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This invention relates generally to the field of homocysteine detection. In particular, the invention provides a method for determining homocysteine presence or concentration in samples, which method comprises: contacting a sample containing or suspected of containing Hcy with a Hcy co-substrate and a Hcy converting enzyme in a Hcy conversion reaction to form a Hcy conversion product and a Hcy co-substrate conversion product; and assessing the Hcy co-substrate conversion product to determine the presence, absence and/or amount of the Hcy in the sample. The Hcy co-substrate conversion product may be assessed directly, or it may be assessed by further conversion of the Hcy co-substrate conversion product into another material by the action of one or more additional enzymes. A kit for assaying homocysteine based on the same principle is also provided.

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Patent Owner(s)

Patent OwnerAddress
DIAZYME LABORATORIES INC3550 GENERAL ATOMICS COURT SAN DIEGO CA 92121

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Datta, Abhijit San Marcos, US 13 132
Dou, Chao San Diego, US 9 12
Yuan, Chong-Sheng San Diego, US 39 219

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