High selectively polymeric adsorbent based on the hydrogen bonding interaction and the use thereof in isolation and purification of active components from gingko biloba extract

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United States of America Patent

PATENT NO 8466298
APP PUB NO 20110218346A1
SERIAL NO

13119371

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Abstract

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Provided are a kind of high selectivity polymeric adsorbents with amide functional groups based on the hydrogen bonding interaction, which is prepared by adequately swelling a DVB-co-MA copolymer of 6% crosslinking degree as the initial resin with dimethyl formamide, performing an amination reaction by adding a diamine, soaking the dried resultant yellow resin with an acylating agent that is a dianhydride, and performing an acylation reaction to obtain the polymeric adsorbent with amide functional groups of the invention. The polymeric adsorbent of the invention can be used to effectively isolate and purify the active ingredients, i.e., flavones and lactones, from the extract of ginkgo leaf.

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NANKAI UNIVERSITY300071 TIANJIN CITY NANKAI DISTRICT WEI JIN ROAD NO 94 MUNICIPAL DISTRICT TIANJIN CITY 300071

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chen, Yingchao Shanghai, CN 7 4
Ren, Ping Langfang, CN 17 9
Shi, Rongfu Tianjin, CN 1 1
Wang, Chunhong Tianjin, CN 4 1
Yuan, Zhi Tianjin, CN 19 32
Zhang, Jing Shanghai, CN 966 8974

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