Methods for determining heptocellular carcinoma subtype and detecting hepatic cancer stem cells
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United States of America Patent
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Jun 18, 2013
Grant Date -
Aug 5, 2010
app pub date -
Jun 9, 2008
filing date -
Jun 8, 2007
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Abstract
The invention provides a method of determining an HCC subtype in a subject comprising a) obtaining a sample from the subject, b) assaying the sample to detect the expression of 1 or more biomarkers, and c) correlating the expression of the biomarkers with an HCC subtype in a subject. The invention further provides methods of detecting HCC stem cells in a sample. Additionally, the invention provides methods and compositions for treating subjects with HCC that take advantage of the biomarkers associated with HCC stem cells.
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