receptor antagonists

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 8461184
APP PUB NO 20100292204A1
SERIAL NO

12844156

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Abstract

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The present invention relates to sulphur containing pyrazole derivatives, and their S-oxidized active metabolites, as selective cannabinoid CB1 receptor antagonists having a high CB1/CB2 receptor subtype selectivity, to methods for the preparation of these compounds, to novel intermediates useful for the synthesis of these pyrazole derivatives, to pharmaceutical compositions comprising one or more of these pyrazole derivatives as active ingredients, as well as to the use of these pharmaceutical compositions for the treatment of psychiatric and neurological disorders. The compounds have the general formula (I)

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Patent Owner(s)

Patent OwnerAddress
ABBVIE B V2132 JD HOOFDDORP

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Kruse, Cornelis G Weesp, NL 66 310
Lange, Josephus H M Weesp, NL 27 110
Vliet, Van Bernard J Weesp, NL 1 2

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