Compositions, splice variants and methods relating to ovarian specific genes and proteins

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United States of America Patent

PATENT NO 8460880
APP PUB NO 20090263411A1
SERIAL NO

12383449

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention relates to newly identified nucleic acid molecules and polypeptides present in normal and neoplastic ovarian cells, including fragments, variants and derivatives of the nucleic acids and polypeptides. The present invention also relates to antibodies to the polypeptides of the invention, as well as agonists and antagonists of the polypeptides of the invention. The invention also relates to compositions containing the nucleic acid molecules, polypeptides, antibodies, agonists and antagonists of the invention and methods for the use of these compositions. These uses include identifying, diagnosing, monitoring, staging, imaging and treating ovarian cancer and non-cancerous disease states in ovarian, identifying ovarian tissue, monitoring and identifying and/or designing agonists and antagonists of polypeptides of the invention. The uses also include gene therapy, production of transgenic animals and cells, and production of engineered ovarian tissue for treatment and research.

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Patent Owner(s)

Patent OwnerAddress
DIAZYME LABORATORIES INC3550 GENERAL ATOMICS COURT SAN DIEGO CA 92121

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chen, Huei-Mei Pleasant Hill, US 12 99
Liu, Shu-Hui Redwood City, US 27 359
Macina, Roberto A San Jose, US 60 241
Sun, Yongming Redwood City, US 105 591
Turner, Leah R Sunnyvale, US 28 194

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