Composition comprising S-allylmercapto-N-acetylcysteine (ASSNAC) for up-regulation of cellular glutathione level

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United States of America Patent

PATENT NO 8455552
APP PUB NO 20110178152A1
SERIAL NO

12597956

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Abstract

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The present invention relates to S-allylmercapto-N-acetylcysteine (ASSNAC) and its pharmaceutically acceptable salts and solvates, which are useful for up-regulation of cellular glutathione levels and expression of phase II detoxifying enzymes. The invention further provides methods of use thereof in the prevention, alleviation or treatment of oxidative stress induced by reactive oxygen species (ROS).

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Patent Owner(s)

Patent OwnerAddress
YEDA RESEARCH AND DEVELOPMENT CO LTD AT THE WEIZMANN INSTITUTE OF SCIENCEP O BOX 95 REHOVOT 76100

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Khenkin, Alex Rehovot, IL 1 9
Mirelman, David Ramat Efal, IL 13 38
Rabinkov, Aharon Rehovot, IL 12 38
Savion, Naphtali Givat Shmuel, IL 10 97

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