Pyrrolopyridine derivatives substituted with cyclic amino group

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United States of America Patent

PATENT NO 8455511
APP PUB NO 20110130364A1
SERIAL NO

12951556

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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An object of the present invention is to provide an antagonist against CRF receptors which is effective as a therapeutic or prophylactic agent for diseases in which CRF is considered to be involved, such as depression, anxiety, Alzheimer's disease, Parkinson's disease, Huntington's chorea, eating disorder, hypertension, gastric diseases, drug dependence, epilepsy, cerebral infarction, cerebral ischemia, cerebral edema, cephalic external wound, inflammation, immunity-related diseases, alopecia, irritable bowel syndrome, sleep disorders, epilepsy, dermatitides, schizophrenia, etc. This problem can be solved with a pyrrolopyrimidine or pyrrolopyridine derivative substituted with a cyclic amino group represented by formula [I] below which has a high affinity for CRF receptors and is effective against diseases in which CRF is considered to be involved.

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Patent Owner(s)

Patent OwnerAddress
TAISHO PHARMACEUTICAL CO LTDTOKYO 170-8633

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bongartz, Jean-Pierre A M Beerse, BE 2 15
De, Bruyn Marcel F L Beerse, BE 9 78
Hendrickx, Robert J M Beerse, BE 4 26
Kennis, Ludo E J Beerse, BE 34 587
Luyckx, Marcel G M Beerse, BE 13 151
Nakazato, Atsuro Tokyo, JP 52 366
Nozawa, Dai Tokyo, JP 52 212
Okubo, Taketoshi Tokyo, JP 38 227
Tamita, Tomoko Tokyo, JP 16 57
Van, Den Keybus Frans M A Beerse, BE 14 84
Van, Roosbroeck Yves E M Beerse, BE 3 31
Yamaguchi, Mikako Tokyo, JP 3 15

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