Rapid two-step synthesis of anti-coagulants

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United States of America Patent

PATENT NO 8450297
APP PUB NO 20060111317A1
SERIAL NO

11204391

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Abstract

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The present invention provides methods for the production of N-deacetylate N-sulfate derivatives of non-sulfated N-acetyl heparosan (HS) polysaccharides, compounds thus obtained and compositions comprising same. This invention also provides applications of N-deacetylate N-sulfate derivatives of non-sulfated N-acetyl heparosan (HS) polysaccharides, and compositions comprising same, for use in controlling coagulation and treating thrombosis.

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Patent Owner(s)

Patent OwnerAddress
MASSACHUSETTS INSTITUTE OF TECHNOLOGYMASSACHUSETTS MASSACHUSETTS

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Balagurunathan, Kuberan Salt Lake City, US 6 40
Rosenberg, Robert D Cambridge, US 22 255

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