Composition exhibiting enhanced formulation stability and delivery of topical active ingredients

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United States of America Patent

PATENT NO 8449918
APP PUB NO 20120015014A1
SERIAL NO

13243189

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Abstract

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A therapeutic, cosmetic or cosmeceutic composition for topical application, capable of stabilizing an active ingredient and delivering the active ingredient, comprising a plurality of microcapsules having a core-shell structure. The microcapsules have a diameter of approximately 0.1 to 100 micron. The core of each microcapsule includes at least one active ingredient, and is encapsulated within a microcapsular shell. The shell is comprised of at least one inorganic polymer obtained by a sol-gel process, and the shell protects the active ingredient before topical application and is designed to release the active ingredient from the microcapsules following application. The composition is useful in encapsulating active ingredients, such as benzoyl peroxide, that are unstable in other formulation, or are irritating to the skin.

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Patent Owner(s)

Patent OwnerAddress
SOL-GEL TECHNOLOGIES LTD74036 NESS ZIONA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Avnir, David Jerusalem, IL 28 908
Gans, Orit Efralm, IL 7 560
Lapidot, Noa Mevasseret Zion, IL 37 838
Magdassi, Shlomo Jerusalem, IL 82 2263
Rottman, Claudi Jerusalem, IL 1 9
Seri-Levy, Alon Rehovot, IL 16 761

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