Crystal structure of the CCZ-LZ domain of NEMO

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United States of America Patent

PATENT NO 8440790
APP PUB NO 20110159598A1
SERIAL NO

12735671

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Abstract

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The invention relates to a crystal of the CC2-LZ domain of the NEMO protein, in which the three-dimensional structure has been determined by X-ray diffraction at a resolution of about 3.25 A. The invention also relates to methods for the crystallization of the CC2-LZ domain. The CC2-LZ crystals and the information derived from the crystalline structures thereof are used for identifying and designing compounds interacting with CC2-LZ.

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Patent Owner(s)

Patent OwnerAddress
INSTITUT PASTEUR75015 PARIS
LES LABORORATOIRES SERVIER35 RUE DE VERDUN SURESNES CEDEX F-92284

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Agou, Fabrice Paris, FR 9 3
Chiaravalli, Jeanne Paris, FR 2 0
Cordier, Florence Aix les Bains, FR 2 12
Duquerroy, Stéphane Paris, FR 4 0
Fontan, Elisabeth Boulogne, FR 1 0
Grubisha, Olivera Surrey, GB 1 0
Kaminska, Monika Dorota Le Plessis Robinson, FR 1 0
Veron, Michel Paris, FR 7 4

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