Compounds, compositions and methods of inhibiting alpha-synuclein toxicity
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United States of America Patent
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May 14, 2013
Grant Date -
Oct 23, 2008
app pub date -
Sep 16, 2005
filing date -
Sep 17, 2004
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Abstract
Compounds and compositions are provided for treatment or amelioration of one or more symptoms of α-synuclein toxicity, α-synuclein mediated diseases or diseases in which α-synuclein fibrils are a symptom or cause of the disease. In one embodiment, the compounds for use in the compositions and methods are heteroaryl acylguanidines, heteroarylhydrazones, dihydropyridones, heteroaryl and aryl styryl ketones, and heteroarylpyrazoles.
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