2-biphenylamino-4-aminopyrimidine derivatives as kinase inhibitors

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United States of America Patent

PATENT NO 8440681
APP PUB NO 20100298295A1
SERIAL NO

12675379

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Abstract

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The invention provides novel pyrimidine derivatives of formula (1) and pharmaceutical compositions thereof, and methods for using such compounds. For example, the pyrimidine derivatives of the invention may be used to treat, ameliorate or prevent a condition which responds to inhibition of insulin-like growth factor (IGF-1R) or anaplastic lymphoma kinase (ALK).

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Patent Owner(s)

Patent OwnerAddress
IRM LLCBERMUDA (UK) HAMILTON

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bursulaya, Badry Escondido, US 29 114
Chen, Bei San Diego, US 110 878
He, Xiaohui San Diego, US 32 335
Lee, Christian Cho-Hua San Diego, US 7 51
Lu, Wenshuo San Diego, US 19 216
Marsilje, Thomas H San Diego, US 19 270

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