Synthetic multimerizing agents

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United States of America Patent

PATENT NO 8436183
APP PUB NO 20120130076A1
SERIAL NO

13361082

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Abstract

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New compounds are disclosed for multimerizing immunophilins and proteins containing immunophilin or immunophilin-related domains. The compounds are of the formula

description='In-line Formulae' end='lead'M-L-Qdescription='In-line Formulae' end='tail'

where M is a synthetic ligand for an FKBP protein.

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Patent Owner(s)

Patent OwnerAddress
ARIAD PHARMACEUTICALS INCMASSACHUSETTS

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Guo, Tao Dayton, US 115 1102
Holt, Dennis A Royersford, US 32 505
Keenan, Terence P Bay Shore, US 24 329
Laborde, Edgardo Foster City, US 25 188
Yang, Wu Princeton, US 109 860

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