2′,2-bisthiazole non-nucleoside compounds, preparation methods, pharmaceutical compositions and uses as hepatitis virus inhibitors thereof

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United States of America Patent

PATENT NO 8426606
APP PUB NO 20130059895A1
SERIAL NO

13636488

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Abstract

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The present disclosure belongs to the field of pharmaceutical chemistry, and relates to a class of 2′,2-bisthiazole non-nucleoside compounds of following formula I, the preparation method and the pharmaceutical composition thereof. The compounds have both the anti-HBV and anti-HCV activities and are useful in treating hepatitides B and C. Pharmacokinetic tests showed the compounds have good bioavailability.

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Patent Owner(s)

Patent OwnerAddress
SHANGHAI INSTITUTE OF MATERIA MEDICA CHINESE ACADEMY OF SCIENCES201203 555 ZHANGJIANG ROAD ZHANGJIANG PUDONG NEW AREA SHANGHAI SHANGHAI CITY SHANGHAI CITY 201203

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Nan, Fajun Shanghai, CN 33 477
Tang, Wei Shanghai, CN 217 3421
Zhang, Yangming Shanghai, CN 16 40
Zuo, Jianping Shanghai, CN 18 101

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