Methods and compositions for modulating tumor cell activity

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United States of America Patent

PATENT NO 8426562
APP PUB NO 20110033471A1
SERIAL NO

12846440

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Abstract

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Antibodies which target clusterin, a protein involved in the epithelial-to-mesenchymal transition of carcinoma cells, are identified and characterized. The antibodies may be used to modulate tumor cell activity through binding the clusterin.

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Patent OwnerAddress
NATIONAL RESEARCH COUNCIL OF CANADA1200 MONTREAL ROAD OTTAWA K1A 0R6

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Cantin, Christiane Pierrefonds, CA 4 44
Lenferink, Anne E G Lorraine, CA 7 14
O'Connor-McCourt, Maureen D Beaconsfield, CA 17 133

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