Arene connected polyamine macrocyclic derivatives, preparation methods and pharmaceutical uses thereof
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United States of America Patent
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Apr 16, 2013
Grant Date -
Jul 15, 2010
app pub date -
May 30, 2008
filing date -
May 30, 2007
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Abstract
The present invention relates to arene connected polyamine macrocyclic derivatives represented by general formula I, pharmaceutically acceptable salts or hydrates thereof which have anti-HIV activities, in which the definitions of substituents are as defined in the description; to preparation methods of the compounds of formula I; to pharmaceutical compositions containing the compounds of formula I or their pharmaceutically acceptable salts or hydrates; to the use of the compounds of formula I or their pharmaceutically acceptable salts or hydrates for the preparation of a medicament for the treatment and prevention of HIV-associated diseases.
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