Methods for diagnosing or treating prostate cancer
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United States of America Patent
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Apr 16, 2013
Grant Date -
Dec 1, 2011
app pub date -
Nov 18, 2009
filing date -
Nov 20, 2008
priority date (Note) -
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Abstract
The present invention provides methods for detecting and/or diagnosing cancer through the determination of the expression level of the STC2 gene. The gene was discovered to discriminate cancer cells from normal cells. Furthermore, the present invention provides methods of screening for therapeutic agents useful in the treatment of cancer, methods for treating cancer. Moreover, the present invention provides double-stranded molecules targeting the STC2 gene, which are suggested to be useful in the treatment of cancer. The compositions and methods of the present invention find particular applicability to prostate cancer, more specifically, castration-resistant prostate cancer and aggressive prostate cancer.
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