Process for the manufacture of laidlomycin
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United States of America Patent
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Apr 9, 2013
Grant Date -
Apr 7, 2011
app pub date -
Sep 22, 2010
filing date -
Oct 5, 2009
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Abstract
Improved process for the isolation of laidlomycin from a fermentation broth includes increasing the pH of the fermentation broth and centrifuging the pH adjusted fermentation broth, resulting in an aqueous layer and a wet solid layer containing laidlomycin. After the aqueous layer is removed, the wet solid layer containing laidlomycin is dried. The process provides an efficient and high yielding method.
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