Method for synthesis of secondary alcohols
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United States of America Patent
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Apr 2, 2013
Grant Date -
Jun 7, 2012
app pub date -
Mar 10, 2011
filing date -
Dec 7, 2010
priority date (Note) -
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status (Latency Note)
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Abstract
A method for synthesis of secondary alcohols is provided for pharmaceutical secondary alcohol by addition of organoboronic acids with aldehydes in presence of the cobalt ion and bidentate ligands as the catalyst. In addition, an enantioselective synthesis method for secondary alcohols is also herein provided in the present invention. The present invention has advantages in using less expensive cobalt ion and commercially available chiral ligands as the catalyst, wide scope of organoboronic acids and aldehydes compatible with this catalytic reaction and achieving excellent yields and/or enantiomeric excess.
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Family
| Country | kind | publication No. | Filing Date |
|---|---|---|---|
| TW | B | TWI396678 | Dec 07, 2010 |
International Classification(s)
- 2011 Application Filing Year
- C07C Class
- 3026 Applications Filed
- 2170 Patents Issued To-Date
- 71.72 % Issued To-Date
Cited Art Landscape
Patent Citation Ranking
- 0 Citation Count
- C07C Class
- 0 % this patent is cited more than
- 12 Age
