Methods of treating inflammatory and autoimmune diseases with alpha-4 inhibitory compounds

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United States of America Patent

PATENT NO 8410115
SERIAL NO

11711874

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Abstract

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Alpha 4 inhibitors are used in treatment of inflammatory and autoimmune diseases, such as multiple sclerosis, Crohn's Disease, rheumatoid arthritis and asthma. Rare occurrences of progressive multifocal leucoencephalopathy during treatment with an alpha-4 agent suggest the possibility that it may be related to such treatment. Monitoring for the JC virus and educating caregivers and patients about the manifestations of progressive multifocal leucoencephalopathy can improve the safety of alpha 4 inhibitor therapy.

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Patent Owner(s)

Patent OwnerAddress
BIOGEN IDEC INTERNATIONAL HOLDING LTDCANON'S COURT 22 VICTORIA STREET HAMILTON HM EX

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Lieberburg, Ivan Berkeley, US 31 550

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