9-(piperazinylalkyl) carbazoles as Bax-modulators
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United States of America Patent
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Apr 2, 2013
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Feb 16, 2012
app pub date -
Sep 6, 2011
filing date -
Oct 18, 1999
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Abstract
Piperazine compounds for use as pharmaceutically active compounds and in pharmaceutical formulations that are useful for the treatment of disorders associated with apoptosis, including neurodegenerative disorders, diseases associated with polyglutamine tracts, epilepsy, ischemia, infertility, cardiovascular disorders, renal hypoxia, hepatitis and AIDS, where the piperazine compounds are represented by formula (I) and the terms R0, R1, R2, R3, k, l, m, n, and X are defined herein:
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