Means and methods for treating or preventing brain tumors based on the nuclear receptor tailless (Tlx)
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United States of America Patent
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Mar 26, 2013
Grant Date -
Feb 17, 2011
app pub date -
Nov 18, 2008
filing date -
Nov 27, 2007
priority date (Note) -
Expired
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Abstract
The present invention relates to the use of an inhibitor of tailless gene expression or tailless protein activity for the preparation of a pharmaceutical composition for treating or preventing the brain tumor in a subject. Preferably an inhibitor of tailless expression is a single or double stranded RNA. An inhibitor of tailless protein activity is preferably an antibody which specifically binds thereto. Finally, the invention includes methods for identifying anti-brain tumor drugs.
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