Synthetic pathway enzymes for the production of argyrins

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United States of America Patent

PATENT NO 8404462
APP PUB NO 20110159537A1
SERIAL NO

12999872

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Abstract

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The invention provides the amino acid sequences comprised in or constituting the synthetic pathway enzymes participating in the production of Argyrins, as well as the nucleic acid sequences encoding the synthetic pathway enzymes participating in the production of Argyrins, as well as genetically manipulated micro-organisms containing nucleic acid sequences encoding the synthetic pathway enzymes for the production of Argyrins, e.g. for inserting one or more of these coding sequences, mutating in a targeted manner one or more of these nucleic acid sequences, in a wild type producer micro-organism or in a heterologous micro-organism, for the production of Argyrins.

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Patent Owner(s)

Patent OwnerAddress
UNIVERSITAET DES SAARLANDESCAMPUS SAARBRUECKEN 66123 SAARBRUECKEN 66123
HEMHOLTZ-ZENTRUM FUER INFEKTIONSFORSCHUNG GMBHINHOFFENSTRASSE 7 BRAUNSCHWEIG 38124

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Garcia, Ronald Saarbrücken, DE 4 0
Müller, Rolf Blieskastel, DE 45 188
Wenzel, Silke Ahnatal, DE 5 19

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