Two types of crystalline of pinocembrin, their preparation and their use for manufacture of pharmaceutical compositions
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United States of America Patent
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Mar 19, 2013
Grant Date -
Sep 1, 2011
app pub date -
Nov 13, 2008
filing date -
Nov 13, 2008
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Abstract
Two crystalline forms of pinocembrin of formula (I): α and β, their preparation and their use for manufacture of pharmaceutical compositions. There exists difference between them in bioavailability. They are used for treating and preventing cerebral ischemic diseases by protective action of neurovascular unit, and enhancing blood drug level in vivo.
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