Anti-platelet membrane glycoprotein VI monoclonal antibody
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United States of America Patent
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Mar 5, 2013
Grant Date -
Sep 8, 2011
app pub date -
Apr 27, 2011
filing date -
Apr 28, 2005
priority date (Note) -
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Abstract
The present invention provides an antibody which has the following features, its active fragment, or a derivative thereof:
- a) It specifically binds to human platelet membrane glycoprotein VI (GPVI);b) The function to activate a platelet and/or the function to induce a thrombocytopenia in vivo are low; andc) It at least partially depletes GPVI on the platelet membrane by contacting with a platelet.
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