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United States of America Patent
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Mar 5, 2013
Grant Date -
Aug 27, 2009
app pub date -
Aug 30, 2006
filing date -
Aug 30, 2005
priority date (Note) -
Expired
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Abstract
The invention relates to a translational recoding reporter construct comprising: a first fluorescent protein coding sequence; a second fluorescent protein coding sequence encoding a fluorescent protein different from the first fluorescent protein; and a linker sequence interposed between the first and second fluorescent protein coding sequence; wherein the first fluorescent protein coding sequence and the second fluorescent protein coding sequence are out-of-frame with respect to each other but are co-expressed as a single fusion polypeptide upon recoding. The invention also relates to methods of use of the construct in screening modulators of recoding.
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