Methods of treating diseases which are mediated by cutaneous lymphocyte antigen positive cells
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United States of America Patent
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Mar 5, 2013
Grant Date -
Sep 1, 2011
app pub date -
Apr 26, 2011
filing date -
Feb 14, 2005
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Abstract
The present invention relates to methods of treating patients suffering from itching and puritis mediated by cutaneous lymphocyte antigen positive T cell. In particular, diseases or disorders including contact dermatitis, drug induced delayed type cutaneous allergic reactions, toxic epidermal necrolysis, cutaneous T cell lymphoma, bullous pemphigoid, alopecia aereata, vitiligo, acne rosacea, prurigo nodularis, and herpes simplex virus, or combination thereof will benefit from the administration of an IL-31 antagonist. The invention also includes methods of predicting a therapeutically responsive patient population.
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