Aryl isoxazole compounds with antitumoural activities
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United States of America Patent
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Feb 26, 2013
Grant Date -
Oct 6, 2011
app pub date -
Jun 30, 2009
filing date -
Jul 4, 2008
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Abstract
The present invention relates to formula I compounds having antitumoural activities through, as one possible biological target, the molecular chaperone heat shock protein 90 (Hsp90) inhibition. The invention includes the use of such compounds in medicine, in relation to cancer disease as well as other diseases where an inhibition of Hsp90 is responsive, and the pharmaceutical compositions containing such compounds.
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