Combination of sPLA2 type IIA mass and OXPL/APOB cardiovascular risk factors for the diagnosis/prognosis of a cardiovascular disease/event

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United States of America Patent

PATENT NO 8383355
APP PUB NO 20130017557A1
SERIAL NO

13498208

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention related to a method of identifying a subject having or at risk of having or developing a cardiovascular disease and/or a cardiovascular event, comprising: —measuring, in a sample obtained from said subject, at least two cardiovascular risk factors: a) sPLA2 type HA mass and b) oxidized phospholipids on apolipoprotein B-IOO particles (OxPL/apoB), —combining said measurements, the combined value of sPLA2 type HA mass and OxPL/apoB being indicative of having or a risk of having or developing a cardiovascular disease and/or cardiovascular event.

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Patent Owner(s)

Patent OwnerAddress
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA1111 FRANKLIN STREET OAKLAND CA 94607-5200
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)75654 PARIS CÉDEX 13

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Mallat, Ziad Paris, FR 28 21
Tedgui, Alain Paris, FR 32 42
Tsimikas, Sotirios La Jolla, US 31 117
Witztum, Joseph La Jolla, US 8 23

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