Antisense formulation
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United States of America Patent
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Feb 26, 2013
Grant Date -
Apr 28, 2011
app pub date -
Jul 13, 2009
filing date -
Jul 18, 2008
priority date (Note) -
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Abstract
A room temperature stable and minimal aggregate liquid formulation comprises an oligonucleotide comprising Seq ID No. 1: or comprising a variant oligonucleotide in which no more than 3 non-sequential bases are different from Seq. ID NO. 1 and an aqueous carrier comprising a aggregation-preventing compound selected from the group consisting of mono and disaccharides and/or sugar alcohols.
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