Method and reagent for measuring nitroreductase enzyme activity
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United States of America Patent
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Feb 19, 2013
Grant Date -
Dec 31, 2009
app pub date -
Jul 10, 2009
filing date -
May 28, 2004
priority date (Note) -
Expired
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Abstract
Disclosed are nitro-substituted squaraine reporter dyes and methods using such dyes for detecting nitroreductase enzyme activity and nitroreductase gene expression in cellular assays. The dyes are of the structure:
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