Antibodies that specifically bind to Aβ oligomers and uses thereof

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United States of America Patent

PATENT NO 8378081
APP PUB NO 20100028357A1
SERIAL NO

12533348

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Abstract

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The present inventors successfully produced monoclonal antibodies that are specific to only soluble Aβ oligomers, but do not recognize soluble Aβ monomers, which are physiological molecules. It was demonstrated that the antibodies are useful as diagnostic/therapeutic monoclonal antibodies for Alzheimer's disease.

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Patent Owner(s)

Patent OwnerAddress
ONCOTHERAPY SCIENCE INCKAWASAKI-SHI KANAGAWA 213-0012

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Matsubara, Etsuro Aomori, JP 8 65
Shibata, Masao Nagano, JP 39 407
Yokoseki, Tatsuki Kanagawa, JP 10 205

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