Process for the synthesis of 9α-hydroxy-steroids
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United States of America Patent
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Feb 5, 2013
Grant Date -
Aug 19, 2010
app pub date -
Jun 30, 2008
filing date -
Jul 4, 2007
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Expired
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Abstract
The present invention relates to a novel selective synthesis of 9α-hydroxy-steroid derivatives of the general formula (I) (I)—wherein the meaning of -A-A′- is —CH2—CH2— or —CH═CH— group—by the bioconversion of compounds of the general formula (II) (II) wherein the meaning of -A-A′- is —CH2—CH2— or —CH═CH— group—by using Nocardia farcinica bacterium strain, deposition number of which is NCAIM (P)—B 001342, as hydroxylating microorganism in the bioconversion.
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